General Hospital Spoilers Thursday, May 21 | GH 05.21.2026 FULL EPISORE

General Hospital (GH) spoilers for Thursday, May 21, reveal that Dante Falconeri (Dominic Zamprogna) will stand up to Lulu Spencer (Alexa Havins Bruening) while Josslyn Jacks (Eden McCoy) catches Cassius Faison aka “Nathan West” (Ryan Paevey) by surprise.

Alexis Davis (Nancy Lee Grahn) will also have some news to share, so let’s discuss what’s ahead.

At the Quartermaine mansion, Alexis will tell Harrison Chase (Josh Swickard) and Brook Lynn Quartermaine (Amanda Setton) that she has a new lead on Phoebe’s (Luna and Lucia Creighton) mother.

Alexis just showed Ava Jerome (Maura West) a picture of Delilah Wilson’s (Lily Cardone) tattoo, which Ava recognized.

Once Ava gives Alexis more information, Alexis will take whatever she’s uncovered to Brook Lynn and Chase.

As for Ethan Lovett (Nathan Dean), he’ll also show up at the Quartermaine mansion to speak with Tracy Quartermaine (Jane Elliot).

Will that lead to Ethan voicing any concerns about Lulu and Rocco Falconeri (Finn Carr)?

Over with Dante, he’ll try to shut down Lulu’s plan to go on the run with Rocco if necessary.

Dante will warn that Lulu will make Rocco a fugitive over his dead body, so she’ll clash with her ex over the best way to keep Rocco safe.

Dante will ultimately get in touch with “Nathan” and perhaps urge him to prove his loyalty.

Maybe Dante will blame “Nathan” for putting this idea to run in Lulu’s head and push the fake detective to block any attempt to flee.

Whatever the case, “Nathan” will be a busy guy in Thursday’s GH episode.

In addition to getting summoned by Dante, it looks like Britt Westbourne (Kelly Thiebaud) may want to meet up with Cassius, too.

Britt may tell Cassius about her plan to leave Port Charles ASAP, but he may warn that the danger won’t go away if she exits.

In fact, Ross Cullum (Andrew Hawkes) could have an even stronger motive to retaliate against Rocco.

Cullum just put it together that Rocco is likely his shooter and the person Jason Morgan (Steve Burton) was protecting on the pier, so Britt may somehow discover this new development soon enough.

At Wyndemere, Lucas Jones (Van Hansis) will face off with Pascal (Marc Forget) again and ask why the butler hasn’t told Jenz Sidwell (Carlo Rota) that he wants Lucas dead so badly.

It’ll be Lucas’ way of pushing Pascal’s buttons, so some tense moments are coming up.

In captivity, Josslyn will eventually ambush Cassius by smashing a chair over him and will try to score a path to freedom.

Cassius may regain the upper hand quickly before Josslyn rants about Anna Devane’s (Finola Hughes) previous stint as a hostage.

Cassius may argue that he wasn’t part of all that, but Josslyn will argue that staying silent and doing nothing makes him just as responsible.

Josslyn will insist Cassius did that to Anna too and will remain disgusted with the whole situation.

As for Nina Reeves (Cynthia Watros) and the injection she was trying to give Jack Brennan (Chris McKenna) when he jolted, fans may soon learn that she moved forward with it despite the scare she got.

General Hospital spoilers suggest Brennan may be stuck in this paralyzed predicament for a while, so stay tuned.